Uses of guanidine hydrochloride

1. It can be used as pharmaceuticals, pesticides, dyes and other organic synthesis intermediates. It can be used to synthesize 2-aminopyrimidine, 2-amino-6-methylpyrimidine, 2-amino-4,6-dimethylpyrimidine, and is used to manufacture sulfadiazine, sulfamethazine, sulfamethazine and other sulfa drugs Intermediate.
2. Guanidine hydrochloride (or guanidine nitrate) reacts with ethyl cyanoacetate to form 2,4-diamino-6-hydroxypyrimidine, which is used to synthesize anti-anemia folic acid. It can also be used as an antistatic agent for synthetic fibers.
3. It can also be used as a protein denaturant.
4. As a strong denaturant in the experiment of extracting total RNA from cells. The guanidine hydrochloride solution can dissolve proteins, leading to cell structure destruction, nuclear protein secondary structure destruction, and dissociation from nucleic acids. In addition, RNase can be inactivated by reducing agents such as guanidine hydrochloride.